Based mostly on the compound’s identified antioxidant and anti inflammatory properties, researchers on the College of Sao Paulo in Brazil got down to consider the results of taurine supplementation as potential antiaging remedy in girls between the ages of 55 and 70.
“Stopping the buildup of free radicals that naturally happens with ageing in all probability prevents cardiovascular illnesses, diabetes and hypertension, amongst different power situations,” Ellen de Freitas, co-principal investigator on the research, stated in an announcement issued by the Sao Paulo Analysis Basis (FAPESP), which supported the venture.
From ox bile to anti-aging
Taurine, which was first remoted by German scientists in 1827 from ox bile, is a semi-essential amino acid present in meat, fish, eggs and seaweed. Naturally occurring within the human physique as properly, it helps digestive, cardiovascular, skeletal, eye, muscular and nervous system features.
“Taurine is an underappreciated, however but necessary method to cardiovascular well being and oxidative stress that’s the hallmark of ageing,” Dr. Mark Miller, president of of Kaiviti Consulting, informed NutraIngredients-USA in reviewing the research.
He added that though taurine has primarily been used as an additive in vitality drinks, the analysis “reaffirms that there are necessary actions on limiting oxidative stress.”
The research authors recommend that taurine’s therapeutic actions in ageing could also be related to its means to scavenge the poisonous results of reactive oxygen species (ROS) that injury cells over time.
“We consider that taurine supplementation could improve the antioxidant protection system and could possibly be a viable dietary technique to stop oxidative injury induced by the ageing course of,” they wrote, noting that antioxidant protection capability and plasma taurine ranges lower in older adults.
Individuals (24 sedentary girls between the ages 55 to 70) within the double-blind randomized medical trial have been administered both 1.5 g of taurine or a corn starch placebo day by day over 16 weeks. Plasma samples collected earlier than and after the intervention have been examined for taurine and oxidative stress markers, together with antioxidant enzymes superoxide dismutase (SOD) and glutathione reductase (GR). Meals consumption, practical capability and blood minerals (selenium, zinc, magnesium and calcium) have been additionally assessed.
“As a major consequence, 16 weeks of taurine supplementation supplied appreciable advantages to oxidative stress markers and elevated plasma taurine focus,” the researchers concluded. Outcomes confirmed a rise in SOD and a discount in malondialdehyde (MDA), a marker for lipid peroxidation.
Subsequent steps: increased dosages
In previous research, the analysis crew has evaluated the results of bigger doses of taurine, starting from 3 g to six g, on younger overweight girls and in younger and wholesome adults. Given the shortage of analysis on taurine within the context of ageing within the scientific literature, the trial used an preliminary low protected dose. Additional research will discover the results of three g per day supplementation on overweight girls between the ages of 60 and 75 with sarcopenia.
101 (2022) 111706
Taurine as a potential antiaging remedy: A managed medical trial on taurine antioxidant exercise in girls ages 55 to 70
Authors: Gabriela Ferreira Abud et al.